Professor Dame Marcela Contreras

Non WS

1. Ref this doc - Link Removed

   1. Had this been a long-standing issue?

   2. How important is publicity in the recruitment of blood donors?

2. Ref this doc - Link Removed

   1. What was the age limit on blood donors at this time / historically?

   2. What were the arguments for/against age exclusion?

   3. Could increasing the age limit earlier have assisted in achieving self-sufficiency?

3. Ref to Ref Removed due to IBI NDA

   1. Regarding para 5.1 - If 0.1% of donors were positive for HTLV-1, would it follow that a Factor VIII concentrate made from the pooled plasma of say even 1,000 - 2,000 donors, would almost certainly be infected with HTLV-1?

   2. What is her understanding of the effect of HTLV-1 on T-Cells and health more generally?

   3. Is it correct that HTLV-1 is sexually transmissible?

   4. Is it correct that HTLV-1 is transmissible via breast milk?

   5. Is she aware of any attempt to inform those who may have been exposed to HTLV-1, their partners and children, all of whom it appears may be at increased risk of a variety of diseases as a result?

   6. The consequences of those unaware of HTLV-1 infection in donating blood and enaging in unprotected sex.

More Non-WS Questions

1. Ref this - Link Removed

   1. Can she expand upon the collection of plasma from unpaid donors being more expensive than paid? Why is this so and to what degree might that incentivise DHSS etc to go for the cheaper option?

   2. Also see - Link Removed

2. Ref - Link Removed

   1. What was involved in a “blood appeal”? How easy were they to organise?

   2. Were they generally successful?

   3. It was relatively straightforward to recruit new/more donors in a particular region when needed?

   4. Was there anything preventing them being done ten, twenty years earlier?